Saggau Lab

Baylor College of Medicine


Selected Publications

Reddy and SaggauAdvanced MP scanning techniques. J. Biomed. Opt.(in press), vol:start-end, 2005.
Hoogland and SaggauFacilitation of L-type Ca2+ channels in dendritic spines by activation of ß2 adrenergic receptors. J. Neuroscience 2004 24(39):8416–8427
Faas, Adwanikar, Gereau, and SaggauPresynaptic calcium modulation by metabotropic glutamate receptor activation: A differential role in acute depression of synaptic transmission and long-term depression. J.Neurosci, 22(16):6885-90. 2002.
Bullen, Patel, and SaggauHigh-speed, random-access fluorescence microscopy: I. High resolution optical recording with voltage-sensitive dyes and ion indicators. Biophys.J., 73:477-491, 1997.

All Publications

Hoogland and SaggauFacilitation of L-type Ca2+ channels in dendritic spines by activation of ß2 adrenergic receptors. J. Neuroscience 2004 24(39):8416–8427
Iyer, Losavio, and SaggauCompensation of spatial and temporal dispersion for acousto-optic multiphoton laser-scanning microscopy. J. Biomed. Opt. 2003 Jul;8(3):460-71.
McQuiston and SaggauMu opioid receptors facilitate the propagation of excitatory activity in rat hippocampal area CA1 by disinhibition of all anatomical layers. J Neurophysiol. 2003 May 15
Levy, Faas, Saggau, Craigen, and SweattMitochondrial regulation of synaptic plasticity in the hippocampus. J Biol Chem. 2003 May 6;278(20):17727-34.
Faas, Adwanikar, Gereau, and SaggauPresynaptic calcium modulation by metabotropic glutamate receptor activation: A differential role in acute depression of synaptic transmission and long-term depression. J.Neurosci, 22(16):6885-90. 2002.
Iyer, Hoogland, Losavio, McQuiston, and SaggauA compact two-photon laser-scanning microscope made from minimally modified commercial components. In: A. Periasamy and P. So (Eds.), Multiphoton Microscopy in the Biomedical Sciences II, Proc. SPIE 4620, 2002.
Sinha and SaggauCharacterization of the spatio-temporal pattern of 4-aminopyridine-induced, GABAA receptor-mediated spontaneous synchronized activity in the hippocampal interneuron network. J.Neurophysiol., 86:381-391, 2001.
Xiong, Saggau, and StringerActivity-dependent intracellular acidification correlates with the duration of seizure activity. J.Neurosci., 20:1290-1296, 2000.
Qian and SaggauActivity-dependent modulation of K+-conductance at presynaptic terminals of a central mammalian synapse. J.Physiol.(Lond.), 519:427-437, 1999.
Qian and SaggauModulation of transmitter release by action potential duration at the hippocampal CA3-CA1 synapse. J.Neurophysiol., 81:288-298, 1999.
Bullen and SaggauHigh-speed, random-access fluorescence microscopy: II. Fast quantitative measurements with voltage-sensitive dyes. Biophys.J. 76:2272-2287, 1999.
Saggau, Bullen, and PatelAcousto-optic random-access laser scanning microscopy: fundamentals and applications to optical recording of neuronal activity. Cell.Mol.Biol. 44:827-846, 1998. Pubmed Link
Bullen, Patel, and SaggauHigh-speed, random-access fluorescence microscopy: I. High resolution optical recording with voltage-sensitive dyes and ion indicators. Biophys.J., 73:477-491, 1997. Pubmed Link
Wu and SaggauPresynaptic inhibition of elicited neurotransmitter release. TINS, 20:204-212, 1997.

Book Contributions

Saggau, Gray, and DaniOptical measurement of calcium signals mediated by ion channels in mammalian presynaptic terminals. In: P.M. Conn (Ed.), Ion Channels, Methods in Enzymology, 294:3-19, Academic Press, 1999. Book Link
Sinha and SaggauOptical imaging with multiple indicators in brain slices. In: R. Schwartz-Bloom (Ed.), Optical Imaging in Living Brain Slices, Methods, 18(2):204-214, Academic Press, 1999.
Bullen and SaggauOptical recording from individual neurons in cell culture. In: H. Johanson and U. Windhorst (Eds.), Modern Techniques in Neuroscience Research, Chapter 4, Springer Verlag, 89-126, 1999.
Sinha and SaggauOptical recording from populations of neurons in brain slices. In: H. Johanson and U. Windhorst (Eds.), Modern Techniques in Neuroscience Research, Chapter 16, Springer Verlag, 459-486, 1999.